• Since 2010:
- CNRS Research Engineer – ICB UMR CNRS 5209 – University of Dijon
• 2008-2009: Post-doctoral position in the Biopolymers Interaction Assembly (BIA) in French National Institute for Agricultural Research (INRA), Nantes, France - Topic: AFM / Fluorescence correlative microscopy for the imaging of biopolymers
• 2005-2008: PhD fellowship awarded by Biocapital Marie Curie Training Network - Johannes Gutenberg University Mainz, Germany - Department of Biology, Institute of Physiological Chemistry and Patobiochemistry and Integrin Advanced Biosystems, Oban,Scotland - Degree: Doctor of Natural Science
PhD thesis: “Isolation and characterization of adhesive molecules from two species of echinoderms Holothuria forskali and Marthasterias glacialis”
• 1999–2004: Master of Science, specialization: Bioorganic Chemistry – Topic: “Synthesis and photochemistry 6-azidopurins” - Adam Mickiewicz University in Poznan, Poland
Research domains
The ANR08 PCV HS-BioAFM project aims to develop the high speed imaging of biomolecules assemblies based on atomic force microscopy (AFM). The project tightly combines technological development and imaging approaches in order to generate a versatile instrument. Imaging at video rate should routinely achieve even on soft biological or organic molecules materials without damage to specimens or artifacts inherent to the design or imaging rates. She had experience and interest in using atomic force microscopy for studying nano-biomaterials and biological interfaces. The ultimate goal of the project is to develop a biosensor for rapid detection of viral pathogens in humans (collaboration with the Institute Curie (Paris), university of Montpellier).
Research training
- Characterisation of food proteins and emulsions by AFM, Fluorescence Microscopy
- Antibody-protein functionalization of AFM tip and surface (mica, glass, silicon wafer)
- Organic synthesis of the linker with purification (chromatography) and identification products (NMR)
- Purification of adhesive proteins by electrophoresis, electro-elution, HPLC, Western Blot, immunoprecipitation, low pressure chromatography (gel filtration), digestion, glass beads
- Characterisation of adhesive protein by AFM, histology, immunohistochemistry
- Measurement of adhesion by AFM and physical methods
- Antibody purification and quantification
- Inorganic and organic synthesis, photochemistry
- Purification organic compound by HPLC, low pressure chromatography
- Analysis products by UV, MS, NMR, IR
Schröder HC; Schlossmacher U; Boreiko A; Natalio F; Baranowska M; Brandt D; Wang X; Tremel W; Wiens M; Müller WE “Silicatein: nanobiotechnological and biomedical applications” Prog Mol Subcell Biol. 2009;47:251-73
Baranowska, M; Müller, WE; Schröder, HC “Isolation and Characterisation Adhesive Secretions from Cuvierian Tubules Holothuria forskali, Echinodermata (Holothuirdea)” submitted
Baranowska, M; Riaublanc A.; Berquand A; Gaillard C.; “Interfacial properties of ß-casein as investigated by AFM and fluorescence microscopy” in preparation
Baranowska, M; Petit M; Freslon N; Gaillard, C “Influence surface charge and linker on adsorption and aggregation ß-casein” in preparation
Baranowska, M ; C.Gaillard “Patent for device to transport AFM tip in liquid” in preparation