CLinical and Innovation Proteomic Platform

Burgundy - Franche Comté proteomic platform CLIPP

Communications

Documents related to the activities of the platform

papers

  • 2012 papersplus
  • 2011 papersplus
  • 2010 papersplus
  • 2009 papersmoins
    • Clinical proteomic
      • Lucchi G, Chambon C, Truntzer C, Pecqueur D, Ducoroy P, Schwartz C, Nicklaus S & Morzel M. (2009). Mass-spectrometry based characterisation of infant whole saliva peptidome. International Journal of Peptide Research and Therapeutics, 15, 177-185
      • Mercedes Quintana, Olivier Palicki, Geraldine Lucchi, Patrick Ducoroy, Christophe Chambon, Christian Salles, Martine Morzel, Inter-individual variability of protein patterns in saliva of healthy adults, Journal of Proteomics, Volume 72, Issue 5, Special Section: \'From Genome to Proteome: Integration and proteome completion\', 21 July 2009, Pages 822-830, ISSN 1874-3919
      • Lehmann S, Roche S, Allory Y, Barthelaix A, Beaudeux JL, Berger F, Betsou F, Borg J, Dupuy A, Garin J, Quillard M, Lizard G, Peoc\'h K, Riviere M, Ducoroy P. Preanalytical guidelines for clinical proteomics investigation of biological fluids. Ann Biol Clin (Paris). 2009 Nov-Dec;67(6):629-39. French
      • Droin N, Hendra JB, Ducoroy P, Solary E. Human defensins as cancer biomarkers and antitumour molecules. J Proteomics. 2009 Aug 20;72(6):918-27. Review.
    • Micro / Nano instrumentation
      • Céline Elie-Caille, Jean-Yves Rauch, Alain Rouleau, Wilfrid Boireau. Preparation of flat gold terraces for protein chip developments. Micro & Nano Letters, 4 (2), 88-94, 2009
      • Dejeu J., Rougeot P., Gauthier M., Boireau W. Adhesions forces controlled by chemical self assembly and pH, application to robotic microhandling. ACS Applied Materials & Interface, 9, 1966-1973, 2009
      • Mangeat T., Berthier A., Elie Caille C., Perrin M., Boireau W., Pieralli C. and Wacogne B. Gold/Silica biochips: applications to Surface Plasmon Resonance and fluorescence quenching. Laser physics, 19(2), 252-58, 2009
      • Jérôme Dejeu, Patrick Rougeot, Michaël Gauthier, Wilfrid Boireau. Reduction of micro-object\'s adhesion using chemical functionalisation. Micro & Nano Letters, 4 (2), 74-79, 2009
      • de Fonseca B, Rossignol J, Bourillot E, Teste P. Influence of the tip effect of a carbon nanostructure on low current electrical arc initiation Materials letters 63(30) (2009) 2611-2614.
      • Flatt RJ, Schober I, Raphael E, Plassard C, Lesniewska E. Conformation of adsorbed comb copolymer dispersants. Langmuir. 2009 Jan 20;25(2):845-55.
      • Douchet G, Sthal F, Bigler E, Bourquin R., Leblois T. Resonant Langasite Microsensor for Atomic Force Microscopy. 2009 JOINT MEETING OF THE EUROPEAN FREQUENCY AND TIME FORUM AND THE IEEE INTERNATIONAL FREQUENCY CONTROL SYMPOSIUM, VOLS 1 AND 2, 826-830.
      • Douchet G, Sthal F, Leblois T, Bigler E., Tellier C., Bourquin R. Study of Langasite crystal Micro-resonators using Length-extension Mode: Temperature-compensated Cuts and Applications to Atomic Force Microscopy. SMART MATERIALS & MICRO/NANOSYSTEMS Book Series: Advances in Science and Technology, 2009, 54, 56-61.
    • Bioreconnaissance moléculaire
      • Boireau W., Rouleau A., Lucchi G., Ducoroy P. Revisited BIA-MS combination: Entire “on-a-chip” processing leading to the proteins identification at low femtomole to sub-femtomole levels. Biosensors Bioelectronics 24 (2009) 1121–1127
      • Pieralli C., Attoui C., Boireau W., Wacogne B. Low Cost Optical Detection of DNA Hybridization on Biochips. Laser physics, 19(2), 259-64, 2009
      • A Erler, S Wegmann, C Elie-Caille, M Maresca, R Seidel, T Heine, DJ Muller, AF Stewart (2009). Conformational adaptability of RedB during DNA annealing and implications for its structural relationship with Rad52. Journal of Molecular Biology, Aug 21;391(3):586-98
    • Biostatistic
      • Mercier C, Truntzer C, Pecqueur D, Gimeno JP, Belz G, Roy P. Mixed-model of ANOVA for measurement reproducibility in proteomics. Journal of Proteomics, 2009, 72, 639-646
  • 2008 papersplus
  • 2007 papersplus
  • 2006 papersplus
  • 2005 papersplus

Patents

  • Patents comprising a contribution from the CLIPP platform:
    • Pazart L., Wacogne B., Pieralli C., Boireau W. et Morel P. « SECURE PERFUSION SYSTEM ». Publication date: 2011-05-12, WO 2011055031.
    • Pazart L., Wacogne B., Pieralli C., Boireau W. et Morel P. « DEVICE FOR TAKING A SAMPLE OF A BODY FLUID AND METHOD FOR IMPLEMENTING SAME ». Publication date: 2011-05-12, WO 2011055029.
    • Wacogne B., Pieralli C., Boireau W., Mangeat T., Coaquette A., Pazart L., Davrinche C., Piranda S., Delforge J.F. « DISPOSABLE DEVICE FOR THE DETECTION OF PARTICLES OF INTEREST, SUCH AS BIOLOGICAL ENTITIES, DETECTION SYSTEM COMPRISING SAID DEVICE AND METHOD FOR USING SAME ». Publication date: 2011-04-07, WO WO2011039430
    • Wacogne Bruno, Pieralli Christian, Boireau Wilfrid, Mangeat Thomas, Coaquette Alain, Pazart Lionel, Davrinche Christian, Piranda Serge, Delforge Jean-François. Disposable device for the detection of particles of interest, such as biological entities, detection system including the aforementioned device and process of implementation . CNRS Patent, 09/04633 from September 29, 2009.
    • Bardiaux Laurent, Boireau Wilfrid, Bourcier Véronique, Krause Claire, Morel Pascal, Pazart Lionel, Pieralli Christian, Wacogne Bruno. « Smart » transfusion device, calles « SmarTTransfuser » . CNRS patent, 09/05330 from November 05, 2009
    • Brevet demande F644/335FR - DISPOSITIF ET PROCEDE DE MANIPULATION ET TRAITEMENT DE CELLULES PAR CHAMP ELECTRIQUE - E. Bourillot, E. Lesniewska.

Récompenses

    • Outstanding Poster Presentation , 2nd International Conference in Bio-sensing Technology, Amsterdam, 10-12 octobre 2011
    • Premier prix poster, Congrès Annuel de Recherche Dermatologique , CARD 2011. Heu Céline, Elie-Caille Céline, Mougey Virginie, Launay Sophie, Nicod Laurence. Involvement of mitochondrial and oxidative mechanisms in glyphosate-induced epidermal cell death. Besançon, 23-24 Juin 2011.
    • Best Paper Award, Biacore & MicroCal User Days. 2010, 2-3 July 2010, Paris (F), Benoît Simon, Sifting on sugar chip of particles with norovirus
    • I.Chouroulinkov reward (1st price) is awarded to poster presented by Magalie Alvergnas at the congress of Cellular Company of Pharmaco-Toxicology which was held the 18 and May 19, 2010 in Paris.

External communications

  • Videos
    • Vidéo on biochips:
    • Presentation of the equipment:

Events

scientifics

SHOW: Micronora 2010
DATE AND PLACE: 28 September - 1st of October 2010 - Besancon
Presence of the CLIPP platform on the Nanozoom stand
Web site

CONGRESS SBCN 2010, 12th International meeting and workshop of the Society for Biochromatography and Nanoseparations
DATE AND PLACE: 19-22 october 2010 Ecole Centrale de Lyon, Ecully, France
TYPE OF PARTICIPATION: Oral communication from Wilfrid Boireau
TITLE OF THE COMMUNICATION: Surface Plasmon Resonance Analysis combined with Mass Spectrometry (SUPRA-MS) for proteomic studies
Web site

CONGRESS ANM 2010, 3rd International Conference on Advanced Nano Materials
DATE AND PLACE: 12-15 September 2010 - Agadir, Morocco
TYPE OF PARTICIPATION: Oral communication from Wilfrid Boireau
TITLE OF THE COMMUNICATION: Nanostructures ceramics for proteomics
TYPE OF PARTICIPATION: Oral communication from Malgorzata Baranowska
TITLE OF THE COMMUNICATION: Interactions between TIO_2 and BSA investigated by AFM and High speed AFM
TYPE OF PARTICIPATION: Oral communication from T. Leblois
TITLE OF THE COMMUNICATION: GAAS as a crystal for biomems: micromachining of the sensing structure
Web site

CONGRESS APCOT 2010, 5th Asia-Pacific Conference on Transducers and Micro-Nano Technology
DATE AND PLACE: 6-9 July 2010 - Perth - Australie (ouest)
TYPE OF PARTICIPATION: Oral communication from C. Elie-Caille
TITLE OF THE COMMUNICATION: Multi-scale characterization of bio-functionalised GaAs crystal plates: towards a performant biosensor
TYPE OF PARTICIPATION: Oral communication from T. Leblois
TITLE OF THE COMMUNICATION: Design of New Lateral Field Excitation GaAs Resonant Biosensors
logoApcot2010

CONGRESS First Cross Border Conference on NanoSciences and Materials for Health. Program
DATE AND PLACE: 21 - 25 June 2010 - Abbaye des Prémontrés, Pont-à-Mousson, France
TYPE OF PARTICIPATION: Invited talk : C. Elie-Caille.
TITLE OF THE COMMUNICATION: Nano-bio-engineering and multiscale characterization of molecular and cellular chips.

CONGRESS BIOSENSORS
DATE AND PLACE: 26 - 28 may 2010 - Glasgow - UK
TYPE OF PARTICIPATION: Oral communication from C. Elie-Caille
TITLE OF THE COMMUNICATION: Development of a batch processed and regenerable GaAs biosensor: Incidence of GaAs crystal plates nanostructuration on surface performance
TYPE OF PARTICIPATION: Oral communication from P. Ducoroy
TITLE OF THE COMMUNICATION: Ligand fishing in human plasma using SPR biosensors and mass spectrometry.
TYPE OF PARTICIPATION: Poster from W. Boireau
TITLE OF THE COMMUNICATION: Nano-bio-engineering on µarrays for the capture of red blood cells in critical transfusional cases.
TYPE OF PARTICIPATION: Poster from W. Boireau
TITLE OF THE COMMUNICATION: On-chip screening of noroviruses using histo-blood group antigens surfaces.
TYPE OF PARTICIPATION: Poster from F. Kardous
TITLE OF THE COMMUNICATION: Improving transfer rate of antibodies on µarrays by using an acoustic transducer with low vibration frequencies.
TYPE OF PARTICIPATION: Poster from C. Frydman
TITLE OF THE COMMUNICATION: On chip multiplex label free bio-affinity analysis and MALDI-MS characterisation of bound analyte.
logobiosensor2010

CONGRESS 42st statistical days
DATE AND PLACE: 24 - 28 may 2010 - Marseille
TYPE OF PARTICIPATION: Oral communication from Elise Mostacci
TITLE OF THE COMMUNICATION: multivariate methods combining wavelets and principal componant analysis for the denoising of mass spectrometry data

CONGRESS Society of Cellular Pharmaco-Toxicology
DATE AND PLACE: 18 - 19 may 2010 in Paris
TYPE OF PARTICIPATION: Poster from Magalie Alvergnas

CONGRESS AFM BioMed
DATE AND PLACE: 12 - 15 may 2010 - Red Island CROATIA
TYPE OF PARTICIPATION: Oral communication from E. Lesniewska
TITLE OF THE COMMUNICATION: Living cells investigated by ultrasound holography.
TYPE OF PARTICIPATION: Oral communication from E. Lesniewska
TITLE OF THE COMMUNICATION: Dynamic of proteo-nucleic complexes.

CONGRESS FORUM 2010 local probe Microscopies
DATE AND PLACE: 15 - 18 march 2010 in Mittelwhir
TYPE OF PARTICIPATION: Oral communication from Maxime Evald
TITLE OF THE COMMUNICATION: Characterization of interactions between proteo-nucleic structures by High-Speed Atomic Force Microscope

Invited conference of Celine Elie-Caille at the 'Nanobiotechnology International Workshop, Protein-surface interaction' , Joint Research Centre (JRC) Ispra (Italy), 2nd - 4 th december 2009. Orale communication : Technological innovations around protein and cell biochip for diagnosis: a translational research from nanoworld to patient.

CLIPP represented at the Congrès ISBS (International Society for Biophysics and imaging of the Skin) 'From Surface to deepness' , (Besancon, 9-12 September 2009). Communication orale de Céline Heu (PhD) : 'Cell imaging connected to protein mapping to investigate glyphosate-induced toxicity on human keratinocytes'

CLIPP représentée au Congress NanoBio-Europe 2009 (Grenoble, 16-18 June 2009).Communications orales: 'Imaging of living epidermal stressed cells by near-field ultrasound holography' (Maxime EWALD) 'Cell nanosensing connected with protein mapping to explore environmental deleterious effects on the skin' (Céline ELIE-CAILLE)

6th days of Functional and operational statistic in Dijon.The conferences will take place the 18 and June 19, 2009 with the Institute of Mathematics of Burgundy
Contacts and registration

SMAP 2009 in Dijon
Organisation of the "Mass spectrometry and proteomic analysis" congress by the CLIPP plateform

Conference of P. Ducoroy for the 1st Inter-Regional Grand-East Conference of oncology translational research, ONCOTRANS 2009 , the 19 and 20 March in Nancy. “Protein chip engineering leading to a revisited concept of BIA-MS: toward a new SPR-MS micro-array platform”

Conference of C. Heu at the Forum 2009 local probe Microscopies from the 16 to the 20 march 2009 in Neufchatel-Hardelot. «Morphological and functional characterization of the consequences of the chemically induced stress oxidizing on a cutaneous cellular model in vitro»

Conference of W. Boireau at the 3rd Day of proteomic Meetings in Angers «innovating techniques in Proteomic », the 20 january 2009.
Program of the day

CLIPP co-organise la 2nde conférence internationale: 'Clinical Proteomics in Oncology' logocpo July 3rd - 4th, 2008, DIJON

CLIPP attends to the 10th World congress on "BIOSENSORS" logobiosensor May 14-16, 2008, SHANGAI

News

Outstanding Poster Presentation , 2nd International Conference in Bio-sensing Technology, Amsterdam, 10-12 octobre 2011

Premier prix poster, Congrès Annuel de Recherche Dermatologique , CARD 2011. Heu Céline, Elie-Caille Céline, Mougey Virginie, Launay Sophie, Nicod Laurence. Involvement of mitochondrial and oxidative mechanisms in glyphosate-induced epidermal cell death. Besançon, 23-24 Juin 2011.

General meeting CLIPP on February 18, 2011 in Dijon.

Best Paper Award, Biacore & MicroCal User Days. 2010, 2-3 July 2010, Paris (F), Benoît Simon, Sifting on sugar chip of particles with norovirus

I.Chouroulinkov reward (1st price) is awarded to poster presented by Magalie Alvergnas at the congress of Cellular Company of Pharmaco-Toxicology which was held the 18 and May 19, 2010 in Paris.

Publication in the newspaper 'En direct' , March 2010
Article :'CLIPP veut révolutionner la protéomique clinique'
Access to the article

Publication in the newspaper 'Temis' , March 26, 2010
Article :La rencontre des technologies et de la recherche clinique
Access to the article (page 7)

The Interregional proteomic Platform CLIPP organizes its first Scientific workshop in Besançon the Tuesday May 26, 09 at the FEMTO-ST Institute , 32 av. de l'Observatoire. With the theme translationnelle research combining the 'nano-world with the patients', 7 lecturers will allow to cover a BROAD set of themes from nano-instrumentation to biological applications with the concern to be understood by an audience of multi-field people (to see program) . To attend to these presentations, it is enough fill this form and to send it back before May 20 by email .

Certification of CLIPP as emerging platform iBISA in 2008

CLIPP in Micronora 113 cover in april 2008PublicationMicronora

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